|
Untitled (Transfect)
|
|
This confocal image is of transfected neonatal rat cardiac fibroblasts expressing fluorescently-tagged DDR2 (Discoidin Domain Receptor 2). The cells are in a collagen thick film, which simulates the extracellular environment. DDR2 is a transmembrane protein, which is thought to be involved in sensing the cell’s local mechanical environment and signaling to the cell the need for remodeling. The blue stain shows the cell nuclei, the green stain shows the actin filaments of the cell cytoskeleton, and the red punctate staining shows the spatial location of the DDR2. (S. Baxter - Mech. Eng., E. Goldsmith - Cell Biology, C. Murphy -Chemistry, C. Robinson – Art; University of South Carolina NanoCenter).
|
|
